Léa Brakier‐Gingras

A Novel Substrate-Based HIV-1 Protease Inhibitor Drug Resistance Mechanism

Monique Nijhuis, Noortje M. van Maarseveen, Stéphane Lastère et al. · PLoS Medicine · 2007 · 166 citations · Full text

Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway

Frédéric Lessard, Sebastian Igelmann, Christian Trahan et al. · Nature Cell Biology · 2018 · 165 citations

Chromatin, Rb Pathway, Cycle Arrest +5

Decreasing the frameshift efficiency translates into an equivalent reduction of the replication of the human immunodeficiency virus type 1

Dominic Dulude, Yamina A. Berchiche, Karine Gendron et al. · Virology · 2005 · 100 citations

Viral Replication, Human Retrovirus, Pathogenesis +11

A mutation in the 530 loop of<i>Escherichia coli</i>16S ribosomal RNA causes resistance to streptomycin

Pierre Melançon, Claude Lemieux, Léa Brakier‐Gingras · Nucleic Acids Research · 1988 · 93 citations · Full text

Ribosomal Rna, Bacteriology, Molecular Biology +16

The three transfer RNAs occupying the A, P and E sites on the ribosome are involved in viral programmed -1 ribosomal frameshift

M.C. Leger, Diane Dulude, Sergey V. Steinberg et al. · Nucleic Acids Research · 2007 · 75 citations · Full text

Viral Replication, Ribosomal Rna, Genetics +21