Jennifer Mariano

Transforming growth factor-β1 is a new form of tumor suppressor with true haploid insufficiency

Binwu Tang, Erwin P. Böttinger, Sonia B. Jakowlew et al. · Nature Medicine · 1998 · 316 citations

Life Sciences, Genetics, Oncology +15

The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

Bo Chen, Jennifer Mariano, Yien Che Tsai et al. · Proceedings of the National Academy of Sciences · 2006 · 207 citations

Life Sciences, Biochemistry, Molecular Biology +14

The ubiquitin ligase gp78 promotes sarcoma metastasis by targeting KAI1 for degradation

Yien Che Tsai, Arnulfo Mendoza, Jennifer Mariano et al. · Nature Medicine · 2007 · 186 citations

Medicine, Molecular Biology, Oncology +13

Allosteric Activation of E2-RING Finger-Mediated Ubiquitylation by a Structurally Defined Specific E2-Binding Region of gp78

Ranabir Das, Jennifer Mariano, Yien Che Tsai et al. · Molecular Cell · 2009 · 164 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

WW Domain HECT E3s Target Cbl RING Finger E3s for Proteasomal Degradation

Alessandra Magnifico, Seth A. Ettenberg, Cuihong Yang et al. · Journal of Biological Chemistry · 2003 · 161 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16