Transforming growth factor-β1 is a new form of tumor suppressor with true haploid insufficiency

Genomic sequencing.

George M. Church, W Gilbert · Proceedings of the National Academy of Sciences · 1984 · 8.2K citations · Full text

Dna Sequencing, Dna, Molecular Biological Method +13

Induction of apoptosis in fibroblasts by c-myc protein

Gérard I. Evan, Andrew H. Wyllie, Christopher S. Gilbert et al. · Cell · 1992 · 3K citations

Fibrosis, Cell Regulation, Apoptosis +7

Targeted disruption of the mouse transforming growth factor-β1 gene results in multifocal inflammatory disease

Marcia M. Shull, Ilona Ormsby, Ann B. Kier et al. · Nature · 1992 · 3K citations · Full text

Inflammation, Autoimmune Disease, Multifocal Inflammatory Disease +9

<i>DPC4</i> , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

Stephan A. Hahn, Mieke Schutte, A.T.M. Shamsul Hoque et al. · Science · 1996 · 2.3K citations

Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death.

A B Kulkarni, C G Huh, Daniel M. Becker et al. · Proceedings of the National Academy of Sciences · 1993 · 1.9K citations · Full text

Null Mice, Lymphocyte Development, T-regulatory Cell +22