Analysis of long-lived <i>C. elegans daf-2</i> mutants using serial analysis of gene expression

Julius Halaschek-Wiener, Jaswinder Khattra, Sheldon McKay, +8

Genome Research

AgingFamily MembersGeneticsMolecular GeneticsGene Regulatory Network +14

The Ras inhibitor S-trans,trans-farnesylthiosalicylic acid chemosensitizes human tumor cells without causing resistance.

Mali Gana‐Weisz, Julius Halaschek-Wiener, Burkhard Jansen, +3

PubMed

Chemoprevention StrategyRas Membrane AnchorageCancer BiologyTumor BiologyOncology +15

Genetic Variations of <i>NAT2</i> and <i>CYP2E1</i> and Isoniazid Hepatotoxicity in a Diverse Population

So Yamada, Mila Tang, Kathryn Richardson, +7

Pharmacogenomics

Reduced telomere length variation in healthy oldest old

Julius Halaschek-Wiener, Irma Vulto, Daniel Fornika, +5

Mechanisms of Ageing and Development

AgingGeriatricsLongevityGeneticsBiogerontology +3

Bcl-2 antisense oligonucleotides chemosensitize human gastric cancer in a SCID mouse xenotransplantation model

Volker Wacheck, Elisabeth Heere‐Ress, Julius Halaschek-Wiener, +4

Journal of Molecular Medicine

Bcl-2 Antisense OligonucleotidesGastrointestinal OncologyMedicinePathologyCancer Genomics +6

Genetic variation in carboxylesterase genes and susceptibility to isoniazid-induced hepatotoxicity

Shinnosuke Yamada, Kathryn Richardson, Mila Tang, +6

The Pharmacogenomics Journal

HepatologyBiochemistryMedicineLiver PhysiologyToxicology +8

A Novel Ras Antagonist Regulates Both Oncogenic Ras and the Tumor Suppressor p53 in Colon Cancer Cells

Julius Halaschek-Wiener, Volker Wacheck, Hermine Schlagbauer‐Wadl, +3

Molecular Medicine

Genetic Variation in Healthy Oldest-Old

Julius Halaschek-Wiener, Mahsa Amirabbasi-Beik, Nasim Monfared, +14

PLoS ONE

AgingAnti-agingGeneticsDisease Susceptibility FactorsBiogerontology +14

Farnesyl Thiosalicylic Acid Chemosensitizes Human Melanoma In Vivo

Julius Halaschek-Wiener, Yoel Kloog, Volker Wacheck, +1

Journal of Investigative Dermatology

Medicinal ChemistryMedicinePhotocarcinogenesisMelanomaDermatology +3

Ras inhibition leads to transcriptional activation of p53 and down-regulation of Mdm2: two mechanisms that cooperatively increase p53 function in colon cancer cells

Julius Halaschek-Wiener, Volker Wacheck, Yoel Kloog, +1

Cellular Signalling

P53 FunctionRas InhibitionMedicineColon Cancer CellsColorectal Cancer +5