Kelly L. Knopp

LY2456302 is a novel, potent, orally-bioavailable small molecule kappa-selective antagonist with activity in animal models predictive of efficacy in mood and addictive disorders

Linda M. Rorick‐Kehn, Jeffrey M. Witkin, Michael A. Statnick et al. · Neuropharmacology · 2013 · 148 citations

Psychoactive Drug, Psychiatry, Functional Selectivity +7

Evidence for the preferential localization of Glutamate Receptor-1 subunits of AMPA receptors to the dendritic spines of medium spiny neurons in rat striatum

Q Chen, L. Veenman, Kelly L. Knopp et al. · Neuroscience · 1998 · 86 citations

Synaptic Plasticity, Dendritic Spines, Neurophysiology +12

Pungency of TRPV1 agonists is directly correlated with kinetics of receptor activation and lipophilicity

Daniel Ursu, Kelly L. Knopp, Bin Liu et al. · European Journal of Pharmacology · 2010 · 69 citations

Molecular Pharmacology, Signal Transduction, Molecular Physiology +9

Tetrodotoxin-Resistant Sodium Channels in Sensory Neurons Generate Slow Resurgent Currents That Are Enhanced by Inflammatory Mediators

Zhi‐Yong Tan, Andrew D. Piekarz, Birgit T. Priest et al. · Journal of Neuroscience · 2014 · 66 citations · Full text

Synaptic Transmission, Neurotransmitter, Neurotransmission +21

Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1<i>S</i>,2<i>S</i>,5<i>R</i>,6<i>S</i>-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures

James A. Monn, Lourdes Prieto, Lorena Taboada et al. · Journal of Medicinal Chemistry · 2015 · 59 citations

Pharmacological Characterization, Pharmacotherapy, Experimental Pharmacology +18