France Carrier

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

Michael B. Kastan, Qimin Zhan, Wafik S. El‐Deiry et al. · Cell · 1992 · 3.1K citations

Genome Instability, Cell Regulation, Cell Death +5

The gadd and MyD genes define a novel set of mammalian genes encoding acidic proteins that synergistically suppress cell growth.

Qian Zhan, K. A. Lord, Isaac Alamo et al. · Molecular and Cellular Biology · 1994 · 481 citations · Full text

Genetics, Cell Proliferation, Myd Genes +20

Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

Qimin Zhan, Michael J. Antinore, Xin Wei Wang et al. · Oncogene · 1999 · 469 citations

P53-regulated Protein Gadd45, Signaling Pathway, Cell Regulation +7

Inhibition of histone deacetylase increases cytotoxicity to anticancer drugs targeting DNA.

Myoung Sook Kim, Mellissa Blake, Jin Hyen Baek et al. · PubMed · 2003 · 464 citations

Histone Modifications, Epigenetic Change, Epigenetics +16

Induction of cellular p53 activity by DNA-damaging agents and growth arrest.

Qimin Zhan, France Carrier, Albert J. Fornace · Molecular and Cellular Biology · 1993 · 433 citations · Full text

Cellular P53 Activity, Dna Damage, Apoptosis +20