GADD45 induction of a G ₂ /M cell cycle checkpoint

Xin Wei Wang, Qimin Zhan, Jill D. Coursen, +7

Proceedings of the National Academy of Sciences

Genomic instability in Gadd45a-deficient mice

M. Christine Hollander, M. Saeed Sheikh, Dmitry V. Bulavin, +13

Nature Genetics

Knockout MouseGenome InstabilityGeneticsDisease Gene IdentificationMedicine +2

Association with Cdc2 and inhibition of Cdc2/Cyclin B1 kinase activity by the p53-regulated protein Gadd45

Qimin Zhan, Michael J. Antinore, Xin Wei Wang, +4

Oncogene

P53-regulated Protein Gadd45Signaling PathwayCell RegulationMedicineTumor Suppressor +5

Interactions between p53 and MDM2 in a mammalian cell cycle checkpoint pathway.

Cheau Yun Chen, Jon Oliner, Qimin Zhan, +3

Proceedings of the National Academy of Sciences

Dna DamageCell DeathMolecular BiologyCell CycleCancer Biology +14

The p53-dependent gamma-ray response of GADD45.

Qimin Zhan, I Bae, Michael B. Kastan, +1

PubMed

Tumor BiologyHalogenated PyrimidinesGliomaOncogenic AgentRadiation Biology +12

Human <b> <i>In vivo</i> </b> Radiation-Induced Biomarkers

Sally A. Amundson, Marcy B. Grace, Christopher B. McLeland, +5

Cancer Research

The GADD45 Inhibition of Cdc2 Kinase Correlates with GADD45-mediated Growth Suppression

Shunqian Jin, Michael J. Antinore, Feng-Di T. Lung, +8

Journal of Biological Chemistry

Central RegionSignal TransductionCell RegulationSignaling PathwayReceptor Tyrosine Kinase +13

Antisense GADD45 expression results in decreased DNA repair and sensitizes cells to u.v.-irradiation or cisplatin.

Smith Ml, Kontny Hu, Qimin Zhan, +3

PubMed

The <i>gadd</i> and <i>MyD</i> Genes Define a Novel Set of Mammalian Genes Encoding Acidic Proteins That Synergistically Suppress Cell Growth

Qimin Zhan, Kenneth A. Lord, Isaac Alamo, +7

Molecular and Cellular Biology

GeneticsCellular PhysiologyTumor BiologyMyeloid NeoplasiaGadd Genes +17

Transcription factors Oct-1 and NF-YA regulate the p53-independent induction of the GADD45 following DNA damage

Shunqian Jin, Feiyue Fan, Wenhong Fan, +6

Oncogene

Genome InstabilityTranscriptional RegulationDna DamageGeneticsApoptosis +7