Basant K. Patel

The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion

Basant K. Patel, Jackie Gavin‐Smyth, Susan W. Liebman · Nature Cell Biology · 2009 · 258 citations · Full text

Transcriptional Regulation, Natural Sciences, Genetics +6

“Prion-proof” for [PIN+]: Infection with In Vitro-made Amyloid Aggregates of Rnq1p-(132–405) Induces [PIN+]

Basant K. Patel, Susan W. Liebman · Journal of Molecular Biology · 2006 · 141 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Pathogenesis +8

Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis

Sei-Kyoung Park, Joo Y. Hong, Fatih Arslan et al. · PLoS Genetics · 2017 · 62 citations · Full text

Apoptosis, Cell Death, Molecular Biology +20

An acridine derivative, [4,5-bis{(N-carboxy methyl imidazolium)methyl}acridine] dibromide, shows anti-TDP-43 aggregation effect in ALS disease models

A. Aditya Prasad, Gembali Raju, Vishwanath Sivalingam et al. · Scientific Reports · 2016 · 53 citations · Full text

Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4

Amandeep Girdhar, Vidhya Bharathi, Vikas Tiwari et al. · International Journal of Biological Macromolecules · 2020 · 49 citations

Liquid-liquid Phase Separation, Protein Function, Biochemistry +9