Vidhya Bharathi

Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4

Amandeep Girdhar, Vidhya Bharathi, Vikas Tiwari et al. · International Journal of Biological Macromolecules · 2020 · 49 citations

Liquid-liquid Phase Separation, Protein Function, Biochemistry +9

Use of<i>ade1</i>and<i>ade2</i>mutations for development of a versatile red/white colour assay of amyloid-induced oxidative stress in<i>saccharomyces cerevisiae</i>

Vidhya Bharathi, Amandeep Girdhar, A. Aditya Prasad et al. · Yeast · 2016 · 37 citations

The amyloidogenicity of a C-terminal region of TDP-43 implicated in Amyotrophic Lateral Sclerosis can be affected by anions, acetylation and homodimerization

A. Aditya Prasad, Vishwanath Sivalingam, Vidhya Bharathi et al. · Biochimie · 2018 · 36 citations

Amyotrophic Lateral Sclerosis, Molecular Neuroscience, C-terminal Region +7

Amyloid-like aggregation of bovine serum albumin at physiological temperature induced by cross-seeding effect of HEWL amyloid aggregates

Sadhana Nirwal, Vidhya Bharathi, Basant K. Patel · Biophysical Chemistry · 2021 · 31 citations

Biochemistry, Protein Folding, Natural Sciences +10

Role of CNC1 gene in TDP-43 aggregation-induced oxidative stress-mediated cell death in S. cerevisiae model of ALS

Vidhya Bharathi, Amandeep Girdhar, Basant K. Patel · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 2021 · 19 citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Apoptosis +8