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Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4

Liquid-liquid Phase SeparationProtein FunctionBiochemistryProtein FoldingTdp-43 ProteinNatural SciencesMolecular BiologyComputational InsightsBiomolecular InteractionProtein MisfoldingProtein Phase SeparationMulti-protein Assembly