Shoichi Okubo

Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40

Yasuaki Itoh, Yuji Kawamata, Masataka Harada et al. · Nature · 2003 · 1.5K citations

Life Sciences, Cell Biology, Endocrinology +16

Discovery of a Novel, Potent, and Orally Active Nonpeptide Antagonist of the Human Luteinizing Hormone-Releasing Hormone (LHRH) Receptor

Nobuo Cho, Masataka Harada, Toshihiro Imaeda et al. · Journal of Medicinal Chemistry · 1998 · 126 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +10

Discovery of a CNS penetrant small molecule SMN2 splicing modulator with improved tolerability for spinal muscular atrophy

Shiori Ando, Shunya Suzuki, Shoichi Okubo et al. · Scientific Reports · 2020 · 39 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +16

Production of Immunoreactive Pituitary Adenylate Cyclase Activating Polypeptide (PACAP) by Human Neuroblastoma Cells, IMR-32: Detection and Characterization with Monoclonal and Polyconal Antibodies against Different Epitopes of PACAP

Nobuhiro Suzuki, Masataka Harada, Chieko Kitada et al. · The Journal of Biochemistry · 1993 · 17 citations

Life Sciences, Biochemistry, Endocrinology +12

A Fragment-Based Approach to Identifying<i>S</i>-Adenosyl-<scp>l</scp>-methionine -Competitive Inhibitors of Catechol<i>O</i>-Methyl Transferase (COMT).

Marion Lanier, Géza Ambrus, Derek C. Cole et al. · Journal of Medicinal Chemistry · 2014 · 12 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17