Patricia K. Lumma

HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins

Paul L. Darke, Ruth F. Nutt, Stephen F. Brady et al. · Biochemical and Biophysical Research Communications · 1988 · 270 citations

Life Sciences, Biochemistry, Molecular Biology +13

A peptide–doxorubicin 'prodrug' activated by prostate-specific antigen selectively kills prostate tumor cells positive for prostate-specific antigen in vivo

Deborah Defeo-Jones, Victor M. Garsky, Bradley K. Wong et al. · Nature Medicine · 2000 · 158 citations

Pharmacy, Oncology, Pharmacology +16

Chemical synthesis of echistatin, a potent inhibitor of platelet aggregation from Echis carinatus: synthesis and biological activity of selected analogs.

V M Garsky, Patricia K. Lumma, Roger Freidinger et al. · Proceedings of the National Academy of Sciences · 1989 · 100 citations · Full text

Medicine, Biochemistry, Pharmacology +17

Organolithium addition to aldehyde dimethylhydrazones: a highly diastereocontrolled synthesis of threo 2-amino alcohols, and (1R,2R)-(-)-norpseudoephedrine

David A. Claremon, Patricia K. Lumma, Brian T. Phillips · Journal of the American Chemical Society · 1986 · 91 citations

Natural Sciences, Chemistry, Medicinal Chemistry +8

The Synthesis of a Prodrug of Doxorubicin Designed to Provide Reduced Systemic Toxicity and Greater Target Efficacy

Victor M. Garsky, Patricia K. Lumma, Dong-Mei Feng et al. · Journal of Medicinal Chemistry · 2001 · 82 citations

Medicine, Oncology, Pharmacology +17