Activation of the Nlrp3 Inflammasome by <i>Streptococcus pyogenes</i> Requires Streptolysin O and NF-κB Activation but Proceeds Independently of TLR Signaling and P2X7 Receptor

Jürgen Harder, Luigi Franchi, Raúl Muñoz-Planillo, +3

The Journal of Immunology

T cell–intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii

Michael H. Shaw, Thornik Reimer, Carmen Sánchez-Valdepeñas, +4

Nature Immunology

Type 1Autoimmune DiseaseAdaptive Immune SystemPathogenesisImmunology +12

Immunogenicity of Whole-Parasite Vaccines against Plasmodium falciparum Involves Malarial Hemozoin and Host TLR9

Cevayir Coban, Yoshikatsu Igari, Masanori Yagi, +13

Cell Host & Microbe

VaccinationPlasmodium FalciparumVaccine TargetMalariaImmunology +7

poly(I:C) and LPS induce distinct IRF3 and NF-κB signaling during type-I IFN and TNF responses in human macrophages

Thornik Reimer, Marija Brcic, Matthias Schweizer, +1

Journal of Leukocyte Biology

Viral Infection Augments Nod1/2 Signaling to Potentiate Lethality Associated with Secondary Bacterial Infections

Yun‐Gi Kim, Jong‐Hwan Park, Thornik Reimer, +6

Cell Host & Microbe

Potentiate Lethality AssociatedHost ResponseViral PersistencePathogenesisImmunology +7

Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhibition

Srimoyee Ghosh, Alexander M. Taylor, Melissa Chin, +33

Journal of Biological Chemistry

Signal TransductionAdaptive Immune SystemT-regulatory CellCbp/ep300 Bromodomain InhibitionImmunology +7

Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome

Thornik Reimer, Michael H. Shaw, Luigi Franchi, +6

European Journal of Immunology

MalariaImmunologyCell DeathPathologyNeuroinflammation +14

Complement C5a potentiates uric acid crystal‐induced IL‐1β production

Ling–Ling An, Payal Mehta, Linda Xu, +7

European Journal of Immunology

Il-1β ReleaseImmunologyImmune RegulationRenal InflammationInnate Immunity +21

Type I IFN Induction in Response to <i>Listeria monocytogenes</i> in Human Macrophages: Evidence for a Differential Activation of IFN Regulatory Factor 3 (IRF3)

Thornik Reimer, Matthias Schweizer, Thomas W. Jungi

The Journal of Immunology

Evidence for involvement of peptidoglycan in the triggering of an oxidative burst by<i>Listeria monocytogenes</i>in phagocytes

Katharina A. Remer, Thornik Reimer, Marija Brcic, +1

Clinical & Experimental Immunology