Raúl Muñoz-Planillo

A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases

Rebecca C. Coll, Avril A. B. Robertson, Jae Jin Chae et al. · Nature Medicine · 2015 · 2.8K citations · Full text

Life Sciences, Immunology, Medicinal Chemistry +15

K+ Efflux Is the Common Trigger of NLRP3 Inflammasome Activation by Bacterial Toxins and Particulate Matter

Raúl Muñoz-Planillo, Peter Kuffa, Giovanny J. Martínez-Colón et al. · Immunity · 2013 · 2.1K citations

Life Sciences, Immunology, Microbiology +16

Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock

Dahai Yang, Yuan He, Raúl Muñoz-Planillo et al. · Immunity · 2015 · 596 citations · Full text

Life Sciences, Cell Biology, Pharmacology +9

Staphylococcus δ-toxin induces allergic skin disease by activating mast cells

Yuumi Nakamura, Jon Oscherwitz, Kemp B. Cease et al. · Nature · 2013 · 539 citations · Full text

Life Sciences, Dermatology, Immunology +12

A Critical Role for Hemolysins and Bacterial Lipoproteins in <i>Staphylococcus aureus</i>-Induced Activation of the Nlrp3 Inflammasome

Raúl Muñoz-Planillo, Luigi Franchi, Lloyd Miller et al. · The Journal of Immunology · 2009 · 331 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17