Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry

Leonardo H. Travassos, Letícia A. M. Carneiro, Mahendrasingh Ramjeet, +13

Nature Immunology

Cell AutophagyMitophagySignal TransductionPlasma MembraneAutoantibody Production +9

Regulated Virulence Controls the Ability of a Pathogen to Compete with the Gut Microbiota

Nobuhiko Kamada, Yun‐Gi Kim, Ho Pan Sham, +4

Science

DysbiosisImmunologyGut MicrobiotaVirulence MechanismsVirulence Genes +14

RICK/RIP2 Mediates Innate Immune Responses Induced through Nod1 and Nod2 but Not TLRs

Jong‐Hwan Park, Yun‐Gi Kim, Christine McDonald, +5

The Journal of Immunology

Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling

Thirumala‐Devi Kanneganti, Mohamed Lamkanfi, Yun‐Gi Kim, +5

Immunity

InflammationToll-like ReceptorsPannexin-1-mediated RecognitionPathogenesisImmunology +8

NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense

Luigi Franchi, Nobuhiko Kamada, Yuumi Nakamura, +6

Nature Immunology

InflammationIl-1β DiscriminatesMucosal ImmunologyMicrobial PathogensMedicine +11

Gut Dysbiosis Promotes M2 Macrophage Polarization and Allergic Airway Inflammation via Fungi-Induced PGE2

Yun‐Gi Kim, Kankanam Gamage Sanath Udayanga, Naoya Totsuka, +3

Cell Host & Microbe

InflammationDysbiosisAllergyInflammatory Lung DiseaseLung Inflammation +11

Distinct Commensals Induce Interleukin-1β via NLRP3 Inflammasome in Inflammatory Monocytes to Promote Intestinal Inflammation in Response to Injury

Sang‐Uk Seo, Nobuhiko Kamada, Raúl Muñoz-Planillo, +10

Immunity

InflammationAllergyMucosal ImmunologyPromote Intestinal InflammationNlrp3 Inflammasome +11

Neonatal acquisition of <i>Clostridia</i> species protects against colonization by bacterial pathogens

Yun‐Gi Kim, Kei Sakamoto, Sang‐Uk Seo, +14

Science

DysbiosisPathogenic MicrobiologyMicrobial PathogensImmunologyNeonatal Acquisition +19

The Cytosolic Sensors Nod1 and Nod2 Are Critical for Bacterial Recognition and Host Defense after Exposure to Toll-like Receptor Ligands

Yun‐Gi Kim, Jong‐Hwan Park, Michael H. Shaw, +3

Immunity

InflammationToll-like ReceptorsHost ResponsePathogenesisImmunology +9

The Nod2 Sensor Promotes Intestinal Pathogen Eradication via the Chemokine CCL2-Dependent Recruitment of Inflammatory Monocytes

Yun‐Gi Kim, Nobuhiko Kamada, Michael H. Shaw, +4

Immunity

InflammationCytokineAutoimmune DiseaseImmunologyInflammatory Monocytes +6