Sunita K. C. Basnet

Discovery of 5‐(2‐(Phenylamino)pyrimidin‐4‐yl)thiazol‐2(3<i>H</i>)‐one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation

Sarah Diab, Theodosia Teo, Malika Kumarasiri et al. · ChemMedChem · 2014 · 80 citations

Highly Potent, Selective, and Orally Bioavailable 4-Thiazol-<i>N</i>-(pyridin-2-yl)pyrimidin-2-amine Cyclin-Dependent Kinases 4 and 6 Inhibitors as Anticancer Drug Candidates: Design, Synthesis, and Evaluation

Solomon Tadesse, Mingfeng Yu, Laychiluh Mekonnen et al. · Journal of Medicinal Chemistry · 2017 · 68 citations · Full text

Chemoprevention Strategy, Pharmacotherapy, Cell Cycle +17

Discovery of 4-(dihydropyridinon-3-yl)amino-5-methylthieno[2,3-d]pyrimidine derivatives as potent Mnk inhibitors: synthesis, structure–activity relationship analysis and biological evaluation

Mingfeng Yu, Peng Li, Sunita K. C. Basnet et al. · European Journal of Medicinal Chemistry · 2015 · 34 citations · Full text

Medicinal Chemistry, Pharmaceutical Chemistry, Biochemistry +9

Pharmacologic Inhibition of MNKs in Acute Myeloid Leukemia

Theodosia Teo, Frankie Lam, Mingfeng Yu et al. · Molecular Pharmacology · 2015 · 29 citations

Inhibition of Mnk enhances apoptotic activity of cytarabine in acute myeloid leukemia cells

Peng Li, Sarah Diab, Mingfeng Yu et al. · Oncotarget · 2016 · 29 citations · Full text

Mixed-phenotype Acute Leukemia, Immunology, Cell Death +16