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Discovery of 4-(dihydropyridinon-3-yl)amino-5-methylthieno[2,3-d]pyrimidine derivatives as potent Mnk inhibitors: synthesis, structure–activity relationship analysis and biological evaluation

Medicinal ChemistryPharmaceutical ChemistryBiochemistryNatural SciencesDrug DiscoveryMedicineRational Drug DesignStructure–activity Relationship AnalysisBiological EvaluationPharmacologyDerivative (Chemistry)Potent Mnk Inhibitors