Frankie Lam

Substituted 4-(Thiazol-5-yl)-2-(phenylamino)pyrimidines Are Highly Active CDK9 Inhibitors: Synthesis, X-ray Crystal Structures, Structure–Activity Relationship, and Anticancer Activities

Hao Shao, Shenhua Shi, Shi‐Liang Huang et al. · Journal of Medicinal Chemistry · 2013 · 124 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

Discovery of 5‐(2‐(Phenylamino)pyrimidin‐4‐yl)thiazol‐2(3<i>H</i>)‐one Derivatives as Potent Mnk2 Inhibitors: Synthesis, SAR Analysis and Biological Evaluation

Sarah Diab, Theodosia Teo, Malika Kumarasiri et al. · ChemMedChem · 2014 · 81 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Synthesis and biological evaluation of imidazo[4,5-b]pyridine and 4-heteroaryl-pyrimidine derivatives as anti-cancer agents

Sherifa Elabar, Frankie Lam, Hao Shao et al. · European Journal of Medicinal Chemistry · 2012 · 76 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Carbene–Metal–Amide Bond Deformation, Rather Than Ligand Rotation, Drives Delayed Fluorescence

Elliot J. Taffet, Yoann Olivier, Frankie Lam et al. · The Journal of Physical Chemistry Letters · 2018 · 76 citations · Full text

Natural Sciences, Chemistry, Physics +17

Highly Potent, Selective, and Orally Bioavailable 4-Thiazol-<i>N</i>-(pyridin-2-yl)pyrimidin-2-amine Cyclin-Dependent Kinases 4 and 6 Inhibitors as Anticancer Drug Candidates: Design, Synthesis, and Evaluation

Solomon Tadesse, Mingfeng Yu, Laychiluh Mekonnen et al. · Journal of Medicinal Chemistry · 2017 · 68 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +13