Eriko Matsuoka

Structure-Based Design of Selective β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: Targeting the Flap to Gain Selectivity over BACE2

Kazuki Fujimoto, Eriko Matsuoka, Naoya Asada et al. · Journal of Medicinal Chemistry · 2019 · 35 citations · Full text

Drug Target, Protein Assembly, Molecular Biology +17

Discovery of novel HIV-1 integrase-LEDGF/p75 allosteric inhibitors based on a pyridine scaffold forming an intramolecular hydrogen bond

Shuichi Sugiyama, Toshiyuki Akiyama, Yoshiyuki Taoda et al. · Bioorganic & Medicinal Chemistry Letters · 2020 · 28 citations

Pyridine Scaffold, Medicinal Chemistry, Intramolecular Hydrogen Bond +11

Structure-Based Approaches to Improving Selectivity through Utilizing Explicit Water Molecules: Discovery of Selective β-Secretase (BACE1) Inhibitors over BACE2

Kazuki Fujimoto, Shuhei Yoshida, Genta Tadano et al. · Journal of Medicinal Chemistry · 2021 · 23 citations · Full text

Crystal structure of the functional region of Uro‐adherence factor A from <i>Staphylococcus saprophyticus</i> reveals participation of the B domain in ligand binding

Eriko Matsuoka, Yoshikazu Tanaka, Makoto Kuroda et al. · Protein Science · 2010 · 19 citations · Full text

Discovery of Extremely Selective Fused Pyridine-Derived β-Site Amyloid Precursor Protein-Cleaving Enzyme (BACE1) Inhibitors with High In Vivo Efficacy through 10s Loop Interactions

Tatsuhiko Ueno, Eriko Matsuoka, Naoya Asada et al. · Journal of Medicinal Chemistry · 2021 · 17 citations · Full text