Sarah M. Skye

A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors

Ina Nemet, Prasenjit Prasad Saha, Nilaksh Gupta et al. · Cell · 2020 · 687 citations · Full text

Inflammation, Gastrointestinal Peptide Hormone, Dysbiosis +13

Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential

Adam Roberts, Xiaodong Gu, Jennifer A. Buffa et al. · Nature Medicine · 2018 · 522 citations · Full text

Inflammation, Thrombosis, Thrombopoiesis +8

Microbial Transplantation With Human Gut Commensals Containing CutC Is Sufficient to Transmit Enhanced Platelet Reactivity and Thrombosis Potential

Sarah M. Skye, Weifei Zhu, Kymberleigh A. Romano et al. · Circulation Research · 2018 · 174 citations · Full text

Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease

Nilaksh Gupta, Jennifer A. Buffa, Adam Roberts et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2020 · 173 citations · Full text

Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk

Xinmin S. Li, Zeneng Wang, Tomáš Čajka et al. · JCI Insight · 2018 · 163 citations · Full text

Metabolomic Profiling, Tmao-producing Nutrient Precursor, Metabolic Syndrome +16