Tyler Lahusen

SIRT2 Maintains Genome Integrity and Suppresses Tumorigenesis through Regulating APC/C Activity

Hyun‐Seok Kim, Athanassios Vassilopoulos, Rui-Hong Wang et al. · Cancer Cell · 2011 · 528 citations · Full text

Suppresses Tumorigenesis, Regulating Apc/c Activity, Cell Regulation +7

Hepatic-Specific Disruption of SIRT6 in Mice Results in Fatty Liver Formation Due to Enhanced Glycolysis and Triglyceride Synthesis

Hyun‐Seok Kim, Cuiying Xiao, Rui-Hong Wang et al. · Cell Metabolism · 2010 · 505 citations

Metabolic Syndrome, Hepatology, Biochemistry +13

SIRT4 Has Tumor-Suppressive Activity and Regulates the Cellular Metabolic Response to DNA Damage by Inhibiting Mitochondrial Glutamine Metabolism

Seung Min Jeong, Cuiying Xiao, Lydia W.S. Finley et al. · Cancer Cell · 2013 · 444 citations · Full text

Reductive Stress, Tumor Biology, Mitochondrial Glutamine Metabolism +10

Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells.

Robert W. Robey, W Y Medina-Pérez, Kenryu Nishiyama et al. · PubMed · 2001 · 342 citations

Chemoprevention Strategy, Atp-binding Cassette Half-transporter, Cancer Biology +16

Phase I Trial of 72-Hour Continuous Infusion UCN-01 in Patients With Refractory Neoplasms

Edward A. Sausville, Susan G. Arbuck, Richard A. Messmann et al. · Journal of Clinical Oncology · 2001 · 294 citations