Gina Leytze

Complementarity determining region 1 (CDR1)- and CDR3-analogous regions in CTLA-4 and CD28 determine the binding to B7-1.

Robert Peach, Jürgen Bajorath, William Brady et al. · The Journal of Experimental Medicine · 1994 · 246 citations · Full text

Adaptive Immune System, T-regulatory Cell, Immunology +18

Covalent Dimerization of CD28/CTLA-4 and Oligomerization of CD80/CD86 Regulate T Cell Costimulatory Interactions

JoAnne L. Greene, Gina Leytze, John Emswiler et al. · Journal of Biological Chemistry · 1996 · 232 citations · Full text

Both Extracellular Immunoglobin-like Domains of CD80 Contain Residues Critical for Binding T Cell Surface Receptors CTLA-4 and CD28

Robert Peach, Jürgen Bajorath, Joseph Naemura et al. · Journal of Biological Chemistry · 1995 · 141 citations · Full text

Interaction of the Cytoplasmic Tail of CTLA-4 (CD152) with a Clathrin-Associated Protein Is Negatively Regulated by Tyrosine Phosphorylation

Jeffrey D. Bradshaw, Pin Lü, Gina Leytze et al. · Biochemistry · 1997 · 122 citations

Molecular Regulation, Immunology, Molecular Biology +19

Binding Stoichiometry of the Cytotoxic T Lymphocyte-associated Molecule-4 (CTLA-4)

Peter S. Linsley, Steven G. Nadler, Jürgen Bajorath et al. · Journal of Biological Chemistry · 1995 · 109 citations · Full text

Signal Transduction, Disulfide Bond, Medicine +11