Bram Herpers

A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies

Sreenivasa Ramaiahgari, Michiel W. den Braver, Bram Herpers et al. · Archives of Toxicology · 2014 · 355 citations

Improved Liver-like Properties, Hepatology, Medicine +10

Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors

Bram Herpers, Berina Eppink, Mark I. James et al. · Nature Cancer · 2022 · 142 citations · Full text

Medicine, Immunology, Tumor Immunity +8

Drosophila patterning is established by differential association of mRNAs with P bodies

Timothy T Weil, Richard M. Parton, Bram Herpers et al. · Nature Cell Biology · 2012 · 130 citations · Full text

Developmental Biology, Developmental Genetics, Genetics +9

Drosophila Squid/hnRNP Helps Dynein Switch from a gurken mRNA Transport Motor to an Ultrastructural Static Anchor in Sponge Bodies

Rénald Delanoue, Bram Herpers, Jan Soetaert et al. · Developmental Cell · 2007 · 116 citations · Full text

Biology, Sponge Bodies, Experimental Biology +8

Restoration of chemosensitivity for doxorubicin and cisplatin in chondrosarcoma in vitro: BCL-2 family members cause chemoresistance

Jolieke G. van Oosterwijk, Bram Herpers, D. W. Meijer et al. · Annals of Oncology · 2011 · 116 citations

Medicine, Metronomic Therapy, Pharmacology +7