Michiel W. den Braver

A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies

Sreenivasa Ramaiahgari, Michiel W. den Braver, Bram Herpers et al. · Archives of Toxicology · 2014 · 355 citations

Improved Liver-like Properties, Hepatology, Medicine +10

Ecotoxicogenomic assessment of diclofenac toxicity in soil

Guangquan Chen, Michiel W. den Braver, Cornelis A.M. van Gestel et al. · Environmental Pollution · 2015 · 62 citations

Ecotoxicity, Diclofenac Toxicity, Toxicology +4

Inter-donor variability of phase I/phase II metabolism of three reference drugs in cryopreserved primary human hepatocytes in suspension and monolayer

Shalenie P. den Braver-Sewradj, Michiel W. den Braver, Nico Vermeulen et al. · Toxicology in Vitro · 2016 · 49 citations

Hepatology, Biochemistry, Medicine +12

Cytochrome P450-Mediated Bioactivation of Mefenamic Acid to Quinoneimine Intermediates and Inactivation by Human Glutathione S-Transferases

Harini Venkataraman, Michiel W. den Braver, Nico Vermeulen et al. · Chemical Research in Toxicology · 2014 · 35 citations

Characterization of cytochrome P450 isoforms involved in sequential two-step bioactivation of diclofenac to reactive p-benzoquinone imines

Michiel W. den Braver, Shalenie P. den Braver-Sewradj, Nico Vermeulen et al. · Toxicology Letters · 2016 · 32 citations

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Chemistry +14