Mark I. James

Curcumin inhibits cancer stem cell phenotypes in ex vivo models of colorectal liver metastases, and is clinically safe and tolerable in combination with FOLFOX chemotherapy

Mark I. James, Chinenye Iwuji, Glen R.B. Irving et al. · Cancer Letters · 2015 · 182 citations · Full text

Medicine, Oncology, Pharmacology +14

Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice

Hong Cai, Edwina N. Scott, Abeer Othman A. Kholghi et al. · Science Translational Medicine · 2015 · 177 citations · Full text

Medicine, Oncology, Pharmacology +17

Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors

Bram Herpers, Berina Eppink, Mark I. James et al. · Nature Cancer · 2022 · 159 citations · Full text

Medicine, Cancer Biology, Oncology +14

Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway

Vicenç Ruiz de Porras, Sara Bystrup, Anna Martínez‐Cardús et al. · Scientific Reports · 2016 · 136 citations · Full text

Medicine, Oncology, Pharmacology +17

Increased Expression of Interleukin-1 Receptor Characterizes Anti-estrogen-Resistant ALDH+ Breast Cancer Stem Cells

Aida Sarmiento-Castro, Eva Caamaño‐Gutiérrez, Andrew H. Sims et al. · Stem Cell Reports · 2020 · 34 citations · Full text

Medicine, Cell Biology, Oncology +17