Colm J. Ryan

ATR inhibitors as a synthetic lethal therapy for tumours deficient in ARID1A

Chris T. Williamson, Rowan Miller, Helen N. Pemberton et al. · Nature Communications · 2016 · 387 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

Hierarchical Modularity and the Evolution of Genetic Interactomes across Species

Colm J. Ryan, Assen Roguev, Kristin L. Patrick et al. · Molecular Cell · 2012 · 248 citations · Full text

Life Sciences, Bioinformatics, Genetics +14

Cells Lacking the <i>RB1</i> Tumor Suppressor Gene Are Hyperdependent on Aurora B Kinase for Survival

Matthew G. Oser, Raquel Fonseca, Abhishek A. Chakraborty et al. · Cancer Discovery · 2018 · 176 citations · Full text

Life Sciences, Genetics, Oncology +17

E-Cadherin/ROS1 Inhibitor Synthetic Lethality in Breast Cancer

Ilirjana Bajrami, Rebecca Marlow, Marieke van de Ven et al. · Cancer Discovery · 2018 · 133 citations · Full text

Medicine, Oncology, Pharmacology +17

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

James Campbell, Colm J. Ryan, Rachel Brough et al. · Cell Reports · 2016 · 109 citations · Full text

Medicine, Molecular Biology, Oncology +17