Homeostatic Levels of p62 Control Cytoplasmic Inclusion Body Formation in Autophagy-Deficient Mice

Masaaki Komatsu, Satoshi Waguri, Masato Koike, +22

Cell

Cell AutophagyMitophagyDevelopmental BiologyAutophagy-deficient MiceAutophagy +8

A Simple Method of Isolating Mouse Aortic Endothelial Cells

Mika Kobayashi, Kenji Inoue, Eiji Warabi, +2

Journal of Atherosclerosis and Thrombosis

AngiogenesisSimple MethodMedicineMurine AortaHuman Tissue +13

Shear stress stabilizes NF-E2-related factor 2 and induces antioxidant genes in endothelial cells: Role of reactive oxygen/nitrogen species

Eiji Warabi, Wakako Takabe, Takashi Minami, +6

Free Radical Biology and Medicine

Endothelial CellsLipid PeroxidationRedox BiologyOxidative StressInflammation +14

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice

Hirokazu Sugimoto, Kosuke Okada, Junichi Shoda, +9

American Journal of Physiology-Gastrointestinal and Liver Physiology

Novel roles of peroxiredoxins in inflammation, cancer and innate immunity

Tetsuro Ishii, Eiji Warabi, Toru Yanagawa

Journal of Clinical Biochemistry and Nutrition

Peroxiredoxin 1Lipid PeroxidationImmunologyImmune RegulationCell Death +17

Ursodeoxycholic acid stimulates Nrf2-mediated hepatocellular transport, detoxification, and antioxidative stress systems in mice

Kosuke Okada, Junichi Shoda, Keiko Taguchi, +13

American Journal of Physiology-Gastrointestinal and Liver Physiology

Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes

Mikako Nishida, Nahoko Yamashita, Taisaku Ogawa, +9

Journal for ImmunoTherapy of Cancer

Essential role of Nrf2 in keratinocyte protection from UVA by quercetin

Shintarou Kimura, Eiji Warabi, Toru Yanagawa, +5

Biochemical and Biophysical Research Communications

Essential RoleBiochemistryMedicinePhotocarcinogenesisPhototoxicity +6

Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet

Kosuke Okada, Eiji Warabi, Hirokazu Sugimoto, +9

Journal of Gastroenterology

InflammationMetabolic SyndromeMetabolic Associated SteatohepatitisMetabolic Associated Steatotic Liver DiseaseNonalcoholic Fatty Liver Disease +13

Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems

Kosuke Okada, Junichi Shoda, Keiko Taguchi, +11

Biochemical and Biophysical Research Communications

ImmunologyCholangiopathiesOxidative StressInflammationHepatotoxicity +14