Hirokazu Sugimoto

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice

Hirokazu Sugimoto, Kosuke Okada, Junichi Shoda et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2009 · 158 citations

Life Sciences, Nutritional Sciences, Pathobiology +17

Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole–imidazole polyamide conjugate

Kiriko Hiraoka, Takahiro Inoue, Rhys Dylan Taylor et al. · Nature Communications · 2015 · 103 citations · Full text

Medicine, Oncology, Pharmacology +17

Runt-related transcription factor 2 (RUNX2) inhibits p53-dependent apoptosis through the collaboration with HDAC6 in response to DNA damage

Toshinori Ozaki, Dan Wu, Hirokazu Sugimoto et al. · Cell Death and Disease · 2013 · 89 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Deletion of Nrf2 leads to rapid progression of steatohepatitis in mice fed atherogenic plus high-fat diet

Kosuke Okada, Eiji Warabi, Hirokazu Sugimoto et al. · Journal of Gastroenterology · 2012 · 87 citations

Veterinary Medicine, Biochemistry, Pathobiology +16

Nrf2 counteracts cholestatic liver injury via stimulation of hepatic defense systems

Kosuke Okada, Junichi Shoda, Keiko Taguchi et al. · Biochemical and Biophysical Research Communications · 2009 · 79 citations

Medicine, Molecular Medicine, Pharmacology +14