Rhys Dylan Taylor

Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole–imidazole polyamide conjugate

Kiriko Hiraoka, Takahiro Inoue, Rhys Dylan Taylor et al. · Nature Communications · 2015 · 103 citations · Full text

Distinct DNA-based epigenetic switches trigger transcriptional activation of silent genes in human dermal fibroblasts

Ganesh N. Pandian, Junichi Taniguchi, Junetha Syed et al. · Scientific Reports · 2014 · 71 citations · Full text

Sequence‐Specific DNA Alkylation Targeting for Kras Codon 13 Mutation by Pyrrole–Imidazole Polyamide <i>seco</i>‐CBI Conjugates

Rhys Dylan Taylor, Sefan Asamitsu, Tomohiro Takenaka et al. · Chemistry - A European Journal · 2013 · 32 citations

Deciphering the genomic targets of alkylating polyamide conjugates using high-throughput sequencing

Anandhakumar Chandran, Junetha Syed, Rhys Dylan Taylor et al. · Nucleic Acids Research · 2016 · 21 citations · Full text

Specific Alkylation of Human Telomere Repeat Sequences by a Tandem-Hairpin Motif of Pyrrole–Imidazole Polyamides with Indole-<i>seco</i>-CBI

Makoto Yamamoto, Toshikazu Bando, Yusuke Kawamoto et al. · Bioconjugate Chemistry · 2014 · 19 citations

Medicinal Chemistry, Pyrrole–imidazole Polyamides, Bioorganic Chemistry +13