Mitsuhiro Makino

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

Kazumasa Miyawaki, Yuichiro Yamada, Nobuhiro Ban et al. · Nature Medicine · 2002 · 941 citations

Obesity, Metabolic Syndrome, Gastric Inhibitory +9

Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor

Noriyasu Kato, Mitsuru Oka, Takayo Murase et al. · Bioorganic & Medicinal Chemistry · 2011 · 85 citations · Full text

Medicinal Chemistry, Pharmacological Characterization, Selective Dpp-iv Inhibitor +13

Loss of kallikrein‐related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice

Kiwami Kidana, Takuya Tatebe, Kaori Ito et al. · EMBO Molecular Medicine · 2018 · 72 citations · Full text

Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats

Noriaki Kato, Kuniharu Mizuno, Mitsuhiro Makino et al. · Diabetes Research and Clinical Practice · 2000 · 59 citations

Metabolic Syndrome, Experimental Diabetic Neuropathy, Medicine +9

Human interferon-α increases immobility in the forced swimming test in rats

Mitsuhiro Makino, Yutaka Kitano, Chika Komiyama et al. · Psychopharmacology · 2000 · 56 citations

Inflammation, Knockout Mouse, Physiology +3