Mitsuhiro Makino

Inhibition of gastric inhibitory polypeptide signaling prevents obesity

Kazumasa Miyawaki, Yuichiro Yamada, Nobuhiro Ban et al. · Nature Medicine · 2002 · 952 citations

Medicine, Biochemistry, Pharmacology +12

Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor

Noriyasu Kato, Mitsuru Oka, Takayo Murase et al. · Bioorganic & Medicinal Chemistry · 2011 · 87 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Loss of kallikrein‐related peptidase 7 exacerbates amyloid pathology in Alzheimer's disease model mice

Kiwami Kidana, Takuya Tatebe, Kaori Ito et al. · EMBO Molecular Medicine · 2018 · 73 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Effects of 15-month aldose reductase inhibition with fidarestat on the experimental diabetic neuropathy in rats

Noriaki Kato, Kuniharu Mizuno, Mitsuhiro Makino et al. · Diabetes Research and Clinical Practice · 2000 · 59 citations

Medicine, Biochemistry, Pharmacology +9

Human interferon-α increases immobility in the forced swimming test in rats

Mitsuhiro Makino, Yutaka Kitano, Chika Komiyama et al. · Psychopharmacology · 2000 · 56 citations

Life Sciences, Immunology, Physiology +8