Mitsuru Oka

Collection, Mapping, and Annotation of Over 28,000 cDNA Clones from <i>japonica</i> Rice

Shoshi Kikuchi, Kouji Satoh, Toshifumi Nagata et al. · Science · 2003 · 867 citations

Life Sciences, Genetics, Plant Biology +14

Ultrahigh resolution drug design. II. Atomic resolution structures of human aldose reductase holoenzyme complexed with fidarestat and minalrestat: Implications for the binding of cyclic imide inhibitors

Ossama El‐Kabbani, Connie Darmanin, T. Schneider et al. · Proteins Structure Function and Bioinformatics · 2004 · 94 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor

Noriyasu Kato, Mitsuru Oka, Takayo Murase et al. · Bioorganic & Medicinal Chemistry · 2011 · 87 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

A highly sensitive assay of human plasma xanthine oxidoreductase activity using stable isotope-labeled xanthine and LC/TQMS

Takayo Murase, Mai Nampei, Mitsuru Oka et al. · Journal of Chromatography B · 2016 · 81 citations

Life Sciences, Biochemistry, Pharmacology +7

Structure of Aldehyde Reductase Holoenzyme in Complex with the Potent Aldose Reductase Inhibitor Fidarestat:  Implications for Inhibitor Binding and Selectivity

Ossama El‐Kabbani, Vincenzo Carbone, Connie Darmanin et al. · Journal of Medicinal Chemistry · 2005 · 73 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17