Jana Janočková

The Antioxidant Additive Approach for Alzheimer’s Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators

Mohamed Benchekroun, Alejandro Romero, Javier Egea et al. · Journal of Medicinal Chemistry · 2016 · 101 citations · Full text

Tacrine Derivatives, Lipid Peroxidation, Redox Biology +17

Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase

Ehab D. AlFadly, Perihan A. Elzahhar, Anna Tramarin et al. · European Journal of Medicinal Chemistry · 2019 · 101 citations · Full text

Alzheimer's Disease, Medicine, Dementia +11

Multitarget‐Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H₃R Antagonism for Neurodegenerative Diseases

Óscar M. Bautista‐Aguilera, Stefanie Hagenow, Alejandra Palomino‐Antolín et al. · Angewandte Chemie International Edition · 2017 · 100 citations

Design, synthesis and biological evaluation of new phthalimide and saccharin derivatives with alicyclic amines targeting cholinesterases, beta-secretase and amyloid beta aggregation

Dawid Panek, Anna Więckowska, Tomasz Wichur et al. · European Journal of Medicinal Chemistry · 2016 · 94 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, New Phthalimide +9

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment

Lukáš Hroch, Patrick Guest, Ondřej Benek et al. · Bioorganic & Medicinal Chemistry · 2016 · 58 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +12