Concepedia

Patrick Guest

PG

6

Publications

1.4K

Citations

6

H-Index

2016

Active since

Affiliations

University of St Andrews(Current)

University Hospital Hradec Králové

University of Hradec Králové

University of Defence

Charles University

Patrick Guest is an author at University of St Andrews specializing in pharmacology, medicine, and drug discovery.

Top concepts

Publications per year

2016–2021

6

Publications

6

Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia

Eliza Yankova, Wesley Blackaby, Mark R. Albertella et al. · Nature · 2021 · 1.2K citations · Full text

, , +9

Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment

Lukáš Hroch, Patrick Guest, Ondřej Benek et al. · Bioorganic & Medicinal Chemistry · 2016 · 58 citations · Full text

, , +12

Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer’s disease treatment

Lukáš Hroch, Ondřej Benek, Patrick Guest et al. · Bioorganic & Medicinal Chemistry Letters · 2016 · 34 citations

, , +8

6-Benzothiazolyl Ureas, Thioureas and Guanidines are Potent Inhibitors of ABAD/17β-HSD10 and Potential Drugs for Alzheimer"s Disease Treatment: Design, Synthesis and in vitro Evaluation

Ondřej Benek, Lukáš Hroch, Laura Aitken et al. · Medicinal Chemistry · 2017 · 27 citations

A scan for genes associated with cancer mortality and longevity in pedigree dog breeds

Aoife Doherty, Inês Lopes, Christopher Ford et al. · Mammalian Genome · 2020 · 21 citations · Full text

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