Che‐Leung Law

cAC10-vcMMAE, an anti-CD30–monomethyl auristatin E conjugate with potent and selective antitumor activity

Joseph A. Francisco, Charles G. Cerveny, Damon L. Meyer et al. · Blood · 2003 · 921 citations

Medicine, Medicinal Chemistry, Oncology +11

CD22 regulates thymus-independent responses and the lifespan of B cells

Kevin L. Otipoby, Kristin B. Andersson, Kevin E. Draves et al. · Nature · 1996 · 390 citations

Life Sciences, Immunology, Molecular Biology +12

Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models

Li Fu, Kim K. Emmerton, Mechthild Jonas et al. · Cancer Research · 2016 · 321 citations

Pharmacy, Oncology, Pharmacology +17

Lysosomal Trafficking and Cysteine Protease Metabolism Confer Target-specific Cytotoxicity by Peptide-linked Anti-CD30-Auristatin Conjugates

May S.K. Sutherland, Russell J. Sanderson, Kristine A. Gordon et al. · Journal of Biological Chemistry · 2006 · 296 citations · Full text

Medicine, Oncology, Pharmacology +16

A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology

Scott C. Jeffrey, Patrick Burke, Robert P. Lyon et al. · Bioconjugate Chemistry · 2013 · 246 citations

Pharmacy, Oncology, Pharmacology +17