Shawn Schiller

A novel antagonist of the prostaglandin E₂ EP₄ receptor inhibits Th1 differentiation and Th17 expansion and is orally active in arthritis models

Q Chen, Kazuyo Muramoto, Nagashima Masaaki et al. · British Journal of Pharmacology · 2010 · 94 citations · Full text

Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin

Galina Kuznetsov, Karen TenDyke, Murray J. Towle et al. · Molecular Cancer Therapeutics · 2009 · 69 citations · Full text

Purified Tubulin, Apoptosis, Cell Death +17

Discovery of anti-inflammatory clinical candidate E6201, inspired from resorcylic lactone LL-Z1640-2, III

Yongchun Shen, Roch P. Boivin, Naoki Yoneda et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 37 citations

Inflammation, Cytokine, Anti-inflammatory +9

FT-6876, a Potent and Selective Inhibitor of CBP/p300, is Active in Preclinical Models of Androgen Receptor-Positive Breast Cancer

Maureen Caligiuri, Grace L. Williams, Jennifer Castro et al. · Targeted Oncology · 2023 · 29 citations · Full text

Design and Optimization of Benzopiperazines as Potent Inhibitors of BET Bromodomains

David S. Millan, Katherine J. Kayser-Bricker, Matthew W. Martin et al. · ACS Medicinal Chemistry Letters · 2017 · 18 citations · Full text