Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet

Chia‐Wei Cheng, Moshe Biton, Adam L. Haber, +27

Cell

ChromatinDevelopmental BiologyMedicineAdult Stem CellCellular Regulatory Mechanism +7

Promotion of Intestinal Epithelial Cell Turnover by Commensal Bacteria: Role of Short-Chain Fatty Acids

Jung-ha Park, Takenori Kotani, Tasuku Konno, +9

PLoS ONE

ProbioticDysbiosisSpf MiceGut MicrobiologyImmunology +12

High-fat diet-activated fatty acid oxidation mediates intestinal stemness and tumorigenicity

Miyeko Mana, Amanda M. Hussey, Constantine N. Tzouanas, +10

Cell Reports

Mitochondrial FaoChemoprevention StrategyPathologyPro-obesity High-fat DietMetabolic Remodeling +15

SOX17 enables immune evasion of early colorectal adenomas and cancers

Norihiro Goto, Peter M.K. Westcott, Saori Goto, +8

Nature

Tumor BiologyImmune EvasionCancer ImmunosurveillanceMedicineImmunology +4

Lymphatics and fibroblasts support intestinal stem cells in homeostasis and injury

Norihiro Goto, Saori Goto, Shinya Imada, +3

Cell stem cell

MedicineStem Cell MobilizationAdult Stem CellImmunologyLymphatic System +5

Inulin diet uncovers complex diet-microbiota-immune cell interactions remodeling the gut epithelium

Renan Oliveira Corrêa, Pollyana Ribeiro Castro, José Luís Fachi, +20

Microbiome

Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Toward Goblet Cells

Shijie He, Peng Lei, Wenying Kang, +22

Gastroenterology

MechanobiologyCell LineageDevelopmental BiologyMedicineAdult Stem Cell +7

Brain metastasis from colorectal cancer: Prognostic factors and survival

Shingo Noura, Masayuki Ohue, Tatsushi Shingai, +8

Journal of Surgical Oncology

Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation

Benjamin E. Mead, Kazuki Hattori, Lauren Levy, +13

Nature Biomedical Engineering

Short-term post-fast refeeding enhances intestinal stemness via polyamines

Shinya Imada, Saleh Khawaled, Heaji Shin, +23

Nature

Developmental BiologyGastroenterologyDigestive TractGut BarrierMedicine