Lou Anne Neilson

Discovery and biochemical characterization of selective ATP competitive inhibitors of the human mitotic kinesin KSP

Keith Rickert, Michael D. Schaber, Maricel Torrent et al. · Archives of Biochemistry and Biophysics · 2007 · 49 citations

Protein Function, Mitochondrial Function, Biochemistry +7

Development of Pyridopyrimidines as Potent Akt1/2 Inhibitors

Zhicai Wu, John C. Hartnett, Lou Anne Neilson et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 25 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +7

Methyl-substitution of an iminohydantoin spiropiperidine β-secretase (BACE-1) inhibitor has a profound effect on its potency

Melissa S. Egbertson, Georgia B. McGaughey, Steven M. Pitzenberger et al. · Bioorganic & Medicinal Chemistry Letters · 2015 · 22 citations

Medicinal Chemistry, Iminohydantoin Spiropiperidine β-Secretase, Biochemistry +10

N , N -Dialkyl-4-[(8-azabicyclo[3.2.1]-oct-3-ylidene)phenylmethyl]benzamides, potent, selective δ opioid agonists

John R. Carson, Steven J. Coats, Ellen E. Codd et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 19 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Medicine +7

Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP

R. M. Garbaccio, Edward S. Tasber, Lou Anne Neilson et al. · Bioorganic & Medicinal Chemistry Letters · 2007 · 18 citations · Full text

Medicine, Natural Sciences, Macromolecular Machine +9