Julie C. Lougheed

Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases

Brigit E. Riley, Julie C. Lougheed, Kari Callaway et al. · Nature Communications · 2013 · 363 citations · Full text

Inhibition of Tumor Cell Growth, Invasion, and Metastasis by EXEL-2880 (XL880, GSK1363089), a Novel Inhibitor of HGF and VEGF Receptor Tyrosine Kinases

Fawn Qian, Stefan Engst, Peiwen Yu et al. · Cancer Research · 2009 · 336 citations

Tumor Cell Growth, Novel Inhibitor, Vegf Receptor 2 +16

Demonstration of a Genetic Therapeutic Index for Tumors Expressing Oncogenic <i>BRAF</i> by the Kinase Inhibitor SB-590885

Alastair J. King, Denis R. Patrick, Roberta S. Batorsky et al. · Cancer Research · 2006 · 262 citations · Full text

Pathology, Oncogenic Braf Alleles, Tumor Biology +17

Novel Carboxamide-Based Allosteric MEK Inhibitors: Discovery and Optimization Efforts toward XL518 (GDC-0973)

Kenneth D. Rice, Naing Aay, Neel K. Anand et al. · ACS Medicinal Chemistry Letters · 2012 · 161 citations · Full text

Drug Target, Erk/map Kinase Cascade, Structural Insight +21

Cabozantinib, a New Standard of Care for Patients With Advanced Renal Cell Carcinoma and Bone Metastases? Subgroup Analysis of the METEOR Trial

Bernard Escudier, Thomas Powles, Robert J. Motzer et al. · Journal of Clinical Oncology · 2018 · 154 citations · Full text

New Standard, Cancer Management, Pharmacotherapy +16