Bruno Rizzuti

Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening

Olga Abián, David Ortega-Alarcón, Ana Jiménez-Alesanco et al. · International Journal of Biological Macromolecules · 2020 · 274 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +10

Identification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma

José L. Neira, Jennifer Bintz, María Pilar Arruebo et al. · Scientific Reports · 2017 · 137 citations · Full text

Drug Target, Engineering, Pathology +16

Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis

Patricia Santofimia‐Castaño, Yi Xia, Wenjun Lan et al. · Journal of Clinical Investigation · 2019 · 100 citations · Full text

Drug Target, Apoptosis, Cell Death +21

Multiple binding modes of ibuprofen in human serum albumin identified by absolute binding free energy calculations

Stefania Evoli, David L. Mobley, Rita Guzzi et al. · Physical Chemistry Chemical Physics · 2016 · 97 citations · Full text

Pharmaceutical Science, Engineering, Albumin Possesses +18

Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs

Bruno Rizzuti, Fedora Grande, Filomena Conforti et al. · Biomedicines · 2021 · 86 citations · Full text