Patricia Santofimia‐Castaño

Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway

Daniel Jiménez-Blasco, Patricia Santofimia‐Castaño, Antonio González et al. · Cell Death and Differentiation · 2015 · 186 citations · Full text

Synaptic Plasticity, Molecular Neuroscience, Neuronal Survival +10

Activation of lysosomal iron triggers ferroptosis in cancer

Tatiana Cañeque, Leeroy Baron, Sebastian Müller et al. · Nature · 2025 · 101 citations · Full text

Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis

Patricia Santofimia‐Castaño, Yi Xia, Wenjun Lan et al. · Journal of Clinical Investigation · 2019 · 100 citations · Full text

Drug Target, Apoptosis, Cell Death +21

NUPR1 inhibitor ZZW-115 induces ferroptosis in a mitochondria-dependent manner

Can Huang, Patricia Santofimia‐Castaño, Xi Liu et al. · Cell Death Discovery · 2021 · 76 citations · Full text

Iron-Sensitive Prodrugs That Trigger Active Ferroptosis in Drug-Tolerant Pancreatic Cancer Cells

Michał Antoszczak, Sebastian Müller, Tatiana Cañeque et al. · Journal of the American Chemical Society · 2022 · 72 citations

Redox Biology, Tumor Biology, Ferroptosis +17