Patricia Santofimia‐Castaño

Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway

Daniel Jiménez-Blasco, Patricia Santofimia‐Castaño, Antonio González et al. · Cell Death and Differentiation · 2015 · 192 citations · Full text

Medicine, Neurobiology, Neuroscience +16

Activation of lysosomal iron triggers ferroptosis in cancer

Tatiana Cañeque, Leeroy Baron, Sebastian Müller et al. · Nature · 2025 · 181 citations · Full text

Life Sciences, Cell Biology, Oncology +16

Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis

Patricia Santofimia‐Castaño, Yi Xia, Wenjun Lan et al. · Journal of Clinical Investigation · 2019 · 104 citations · Full text

Pharmacy, Oncology, Pharmacology +15

NUPR1 inhibitor ZZW-115 induces ferroptosis in a mitochondria-dependent manner

Can Huang, Patricia Santofimia‐Castaño, Xi Liu et al. · Cell Death Discovery · 2021 · 82 citations · Full text

Medicine, Oncology, Pharmacology +17

Iron-Sensitive Prodrugs That Trigger Active Ferroptosis in Drug-Tolerant Pancreatic Cancer Cells

Michał Antoszczak, Sebastian Müller, Tatiana Cañeque et al. · Journal of the American Chemical Society · 2022 · 77 citations

Medicine, Oncology, Pharmacology +17