Can Huang

Co-delivery of cisplatin and paclitaxel by folic acid conjugated amphiphilic PEG-PLGA copolymer nanoparticles for the treatment of non-small lung cancer

Zelai He, Jingwen Huang, Yuanyuan Xu et al. · Oncotarget · 2015 · 106 citations · Full text

Ligand-based design identifies a potent NUPR1 inhibitor exerting anticancer activity via necroptosis

Patricia Santofimia‐Castaño, Yi Xia, Wenjun Lan et al. · Journal of Clinical Investigation · 2019 · 100 citations · Full text

Drug Target, Apoptosis, Cell Death +21

Thermoresponsive nanocomposite gel for local drug delivery to suppress the growth of glioma by inducing autophagy

Li Ding, Qi Wang, Ming Shen et al. · Autophagy · 2017 · 79 citations · Full text

Nanoparticles, Engineering, Biomedical Engineering +17

NUPR1 inhibitor ZZW-115 induces ferroptosis in a mitochondria-dependent manner

Can Huang, Patricia Santofimia‐Castaño, Xi Liu et al. · Cell Death Discovery · 2021 · 76 citations · Full text

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

Wenjun Lan, Patricia Santofimia‐Castaño, Mirna Swayden et al. · JCI Insight · 2020 · 49 citations · Full text

Reductive Stress, Genome Instability, Oncogenic Agent +15