John Quin

Pyrido[2,3-<i>d</i>]pyrimidin-7-ones as Specific Inhibitors of Cyclin-Dependent Kinase 4

Scott N. VanderWel, Patricia J. Harvey, Dennis J. McNamara et al. · Journal of Medicinal Chemistry · 2005 · 149 citations · Full text

Medicine, Medicinal Chemistry, Oncology +16

Design and synthesis of potent, selective, and orally active fluorine-containing renin inhibitors

Annette M. Doherty, Ila Sircar, Brian E. Kornberg et al. · Journal of Medicinal Chemistry · 1992 · 62 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

4-Anilino-5-carboxamido-2-pyridone Derivatives as Noncompetitive Inhibitors of Mitogen-Activated Protein Kinase Kinase

Julie A. Spicer, Gordon W. Rewcastle, Michael D. Kaufman et al. · Journal of Medicinal Chemistry · 2007 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Binding thermodynamics of substituted diaminopyrimidine renin inhibitors

Ronald W. Sarver, Jeanette Peevers, Wayne L. Cody et al. · Analytical Biochemistry · 2006 · 41 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Synthesis and structure–activity relationships of N-6 substituted analogues of 9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of Wee1 and Chk1 checkpoint kinases

Jeff B. Smaill, Edward N. Baker, R J Booth et al. · European Journal of Medicinal Chemistry · 2007 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14