Jamel Meslamani

BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice

Ka‐Lung Cheung, Geming Lu, Rajal Sharma et al. · Proceedings of the National Academy of Sciences · 2017 · 128 citations · Full text

Protein–Ligand-Based Pharmacophores: Generation and Utility Assessment in Computational Ligand Profiling

Jamel Meslamani, Jiabo Li, Jon M. Sutter et al. · Journal of Chemical Information and Modeling · 2012 · 119 citations

sc-PDB: a database for identifying variations and multiplicity of ‘druggable’ binding sites in proteins

Jamel Meslamani, Didier Rognan, Esther Kellenberger · Bioinformatics · 2011 · 105 citations

Spatially constrained tandem bromodomain inhibition bolsters sustained repression of BRD4 transcriptional activity for TNBC cell growth

Chunyan Ren, Guangtao Zhang, Fangbin Han et al. · Proceedings of the National Academy of Sciences · 2018 · 68 citations · Full text

Discovery and Lead-Optimization of 4,5-Dihydropyrazoles as Mono-Kinase Selective, Orally Bioavailable and Efficacious Inhibitors of Receptor Interacting Protein 1 (RIP1) Kinase

Philip A. Harris, Nicolas Faucher, Nicolas George et al. · Journal of Medicinal Chemistry · 2019 · 68 citations · Full text

Drug Target, Immunology, Efficacious Inhibitors +19