Nicolas Triballeau

Virtual Screening Workflow Development Guided by the “Receiver Operating Characteristic” Curve Approach. Application to High-Throughput Docking on Metabotropic Glutamate Receptor Subtype 4

Nicolas Triballeau, Francine Acher, Isabelle Brabet et al. · Journal of Medicinal Chemistry · 2005 · 621 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Discovery of 2-[[2-Ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2- <i>a</i> ]pyridin-3-yl]methylamino]-4-(4-fluorophenyl)thiazole-5-carbonitrile (GLPG1690), a First-in-Class Autotaxin Inhibitor Undergoing Clinical Evaluation for the Treatment of Idiopathic Pulmonary Fibrosis

Nicolas Desroy, Christopher Housseman, Xavier Bock et al. · Journal of Medicinal Chemistry · 2017 · 139 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +8

Discovery and Optimization of an Azetidine Chemical Series As a Free Fatty Acid Receptor 2 (FFA2) Antagonist: From Hit to Clinic

Mathieu Pizzonero, Sonia Dupont, Marielle Babel et al. · Journal of Medicinal Chemistry · 2014 · 110 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Closure of the Venus flytrap module of mGlu8 receptor and the activation process: Insights from mutations converting antagonists into agonists

Anne‐Sophie Bessis, Philippe Rondard, Florence Gaven et al. · Proceedings of the National Academy of Sciences · 2002 · 107 citations

Life Sciences, Molecular Biology, Neuroscience +16

Discovery of Diarylhydantoins as New Selective Androgen Receptor Modulators

F. Nique, Séverine Hebbe, Christophe Peixoto et al. · Journal of Medicinal Chemistry · 2012 · 79 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +17