Eric T. Sun

Discovery of the Macrocycle 11-(2-Pyrrolidin-1-yl-ethoxy)-14,19-dioxa-5,7,26-triaza-tetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8,10,12(27),16,21,23-decaene (SB1518), a Potent Janus Kinase 2/Fms-Like Tyrosine Kinase-3 (JAK2/FLT3) Inhibitor for the Treatment of Myelofibrosis and Lymphoma

Anthony D. William, Angeline C.-H. Lee, Stéphanie Blanchard et al. · Journal of Medicinal Chemistry · 2011 · 194 citations · Full text

Janus Kinase 2, Pharmacotherapy, Tumor Biology +19

Synthesis of analogs of the carboxyl protease inhibitor pepstatin. Effect of structure on inhibition of pepsin and renin

Daniel H. Rich, Eric T. Sun, E H Ulm · Journal of Medicinal Chemistry · 1980 · 133 citations · Full text

TG02, a novel oral multi-kinase inhibitor of CDKs, JAK2 and FLT3 with potent anti-leukemic properties

K C Goh, Veronica Novotny‐Diermayr, Stefan Hart et al. · Leukemia · 2011 · 128 citations

Medicine, Receptor Tyrosine Kinase, Malignant Blood Disorder +9

Discovery of Kinase Spectrum Selective Macrocycle (16<i>E</i>)-14-Methyl-20-oxa-5,7,14,26-tetraazatetracyclo[19.3.1.1(2,6).1(8,12)]heptacosa-1(25),2(26),3,5,8(27),9,11,16,21,23-decaene (SB1317/TG02), a Potent Inhibitor of Cyclin Dependent Kinases (CDKs), Janus Kinase 2 (JAK2), and Fms-like Tyrosine Kinase-3 (FLT3) for the Treatment of Cancer

Anthony D. William, Angeline C.-H. Lee, Kee Chuan Goh et al. · Journal of Medicinal Chemistry · 2011 · 99 citations · Full text

Immunology, Janus Kinase 2, Oral Efficacy +17

Synthesis of (3S,4S)-4-amino-3-hydroxy-6-methylheptanoic acid derivatives. Analysis of diastereomeric purity

Daniel H. Rich, Eric T. Sun, A.S. Boparai · The Journal of Organic Chemistry · 1978 · 93 citations

Derivative (Chemistry), Bioorganic Chemistry, Derivatives +13