Frédéric St-Jean

Pyrimidoaminotropanes as Potent, Selective, and Efficacious Small Molecule Kinase Inhibitors of the Mammalian Target of Rapamycin (mTOR)

Anthony A. Estrada, Daniel G. Shore, Elizabeth Blackwood et al. · Journal of Medicinal Chemistry · 2013 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis of Akt Inhibitor Ipatasertib. Part 2. Total Synthesis and First Kilogram Scale-up

Travis Remarchuk, Frédéric St-Jean, Diane E. Carrera et al. · Organic Process Research & Development · 2014 · 26 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14

Manufacture of the PI3K β-Sparing Inhibitor Taselisib. Part 2: Development of a Highly Efficient and Regioselective Late-Stage Process

Frédéric St-Jean, Travis Remarchuk, Rémy Angelaud et al. · Organic Process Research & Development · 2019 · 16 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13

Quantitation of a Ketone Enolization and a Vinyl Sulfonate Stereoisomer Formation Using Inline IR Spectroscopy and Modeling

Kallakuri Suparna Rao, Frédéric St-Jean, Archana Kumar · Organic Process Research & Development · 2019 · 16 citations

Natural Sciences, Chemistry, Organic Chemistry +15

Manufacture of the PI3K β-Sparing Inhibitor Taselisib. Part 1: Early-Stage Development Routes to the Bromobenzoxazepine Core

Travis Remarchuk, Rémy Angelaud, David Askin et al. · Organic Process Research & Development · 2019 · 15 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13