David Askin

On the scope, mechanism and stereochemistry of the Lewis acid catalyzed cyclocondensation of activated dienes with aldehydes: an application to the erythronolide problem

Samuel J. Danishefsky, Eric R. Larson, David Askin et al. · Journal of the American Chemical Society · 1985 · 170 citations

Activated Dienes, Molecular Sciences, Bioorganic Chemistry +13

First Generation Process for the Preparation of the DPP-IV Inhibitor Sitagliptin

Karl B. Hansen, Jaume Balsells, Spencer D. Dreher et al. · Organic Process Research & Development · 2005 · 158 citations

Dpp-iv Inhibitor Sitagliptin, Medicinal Chemistry, Pharmaceutical Science +14

Highly diastereoselective reaction of a chiral, non-racemic amide enolate with (S)-glycidyl tosylate. Synthesis of the orally active HIV-1 protease inhibitor L-735,524

David Askin, Kan K. Eng, Kai Rossen et al. · Tetrahedron Letters · 1994 · 149 citations

Diastereoselective Reaction, Medicinal Chemistry, -Glycidyl Tosylate +11

A highly catalytic robust palladium catalyzed cyanation of aryl bromides

Peter E. Maligres, Marjorie S. Waters, Fred J. Fleitz et al. · Tetrahedron Letters · 1999 · 147 citations

Chemical Engineering, Engineering, Catalytic Robust Palladium +4

Nosylaziridines: Activated aziridine electrophiles

Peter E. Maligres, Marjorie M. See, David Askin et al. · Tetrahedron Letters · 1997 · 110 citations

Pharmacology, Organic Chemistry, Organic Electrochemistry +1