Kan K. Eng

Highly diastereoselective reaction of a chiral, non-racemic amide enolate with (S)-glycidyl tosylate. Synthesis of the orally active HIV-1 protease inhibitor L-735,524

David Askin, Kan K. Eng, Kai Rossen et al. · Tetrahedron Letters · 1994 · 149 citations

Pharmacy, Medicinal Chemistry, Pharmacology +6

Highly Regioselective Friedländer Annulations with Unmodified Ketones Employing Novel Amine Catalysts:  Syntheses of 2-Substituted Quinolines, 1,8-Naphthyridines, and Related Heterocycles

Peter G. Dormer, Kan K. Eng, Roger N. Farr et al. · The Journal of Organic Chemistry · 2002 · 132 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17

Diastereoselective syn-epoxidation of 2-alkyl-4-enamides to epoxyamides: Synthesis of the Merck HIV-1 protease inhibitor epoxide intermediate

Peter E. Maligres, Veena Upadhyay, Kai Rossen et al. · Tetrahedron Letters · 1995 · 69 citations

Pharmacy, Medicinal Chemistry, Pharmacology +8

An efficient asymmetric synthesis of (R)-3-amino-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-one

Joseph D. Armstrong, Kan K. Eng, Jennifer Keller et al. · Tetrahedron Letters · 1994 · 55 citations

Pharmacy, Chemistry, Medicinal Chemistry +9

A short total synthesis of (.+-.)-gephyrotoxin-223AB

Chris A. Broka, Kan K. Eng · The Journal of Organic Chemistry · 1986 · 54 citations

Natural Sciences, Biochemistry, Chemistry +8