Concepedia

Michael D. Croghan

MD

Statistics

Publications

11

Citations

338

H-Index

10

Active since

2003

Affiliations

Amgen (United States)(Current)

Michael D. Croghan is an author at Amgen (United States) specializing in drug discovery, medicine, and pharmacology.

Top concepts

Publications per year

2003–2015

11

Publications

11

Design and Preparation of a Potent Series of Hydroxyethylamine Containing β-Secretase Inhibitors That Demonstrate Robust Reduction of Central β-Amyloid

Matthew M. Weiss, Toni Williamson, Safura Babu‐Khan et al. · Journal of Medicinal Chemistry · 2012 · 63 citations · Full text

Design of a new peptidomimetic agonist for the melanocortin receptors based on the solution structure of the peptide ligand, Ac-Nle-cyclo[Asp-Pro-dPhe-Arg-Trp-Lys]-NH2

Christopher Fotsch, D.M. Smith, Jeffrey A. Adams et al. · Bioorganic & Medicinal Chemistry Letters · 2003 · 42 citations · Full text

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Design and Synthesis of Potent, Orally Efficacious Hydroxyethylamine Derived β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors

Thomas A. Dineen, Matthew M. Weiss, Toni Williamson et al. · Journal of Medicinal Chemistry · 2012 · 41 citations · Full text

, , +19

Discovery and Structure-Guided Optimization of Diarylmethanesulfonamide Disrupters of Glucokinase–Glucokinase Regulatory Protein (GK–GKRP) Binding: Strategic Use of a N → S (n<sub>N</sub> → σ*<sub>S–X</sub>) Interaction for Conformational Constraint

Lewis D. Pennington, Michael D. Bartberger, Michael D. Croghan et al. · Journal of Medicinal Chemistry · 2015 · 38 citations · Full text

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Small Molecule Disruptors of the Glucokinase–Glucokinase Regulatory Protein Interaction: 1. Discovery of a Novel Tool Compound for in Vivo Proof-of-Concept

Kate S. Ashton, Kristin L. Andrews, Marion C. Bryan et al. · Journal of Medicinal Chemistry · 2014 · 33 citations · Full text

, , +21

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