Matthew S. Winston

Statistics

Publications

Citations

275

H-Index

Active since

2022

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Matthew S. Winston is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in enzymology, catalytic mechanisms, and biocatalysis.

ORCID

Publications per year

2022–2024

Publications

A kinase-cGAS cascade to synthesize a therapeutic STING activator

John A. McIntosh, Zhijian Liu, Brian M. Andresen et al. · Nature · 2022 · 135 citations

Life Sciences, Molecular Biology, Pharmacology +10

Engineering Hydroxylase Activity, Selectivity, and Stability for a Scalable Concise Synthesis of a Key Intermediate to Belzutifan

Wai Ling Cheung‐Lee, Joshua N. Kolev, John A. McIntosh et al. · Angewandte Chemie International Edition · 2024 · 53 citations · Full text

Engineering, Biochemistry, Biotechnology +16

Diverse Catalytic Reactions for the Stereoselective Synthesis of Cyclic Dinucleotide MK-1454

Tamas Benkovics, Feng Peng, Eric M. Phillips et al. · Journal of the American Chemical Society · 2022 · 45 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Transaminase-Catalyzed Synthesis of β-Branched Noncanonical Amino Acids Driven by a Lysine Amine Donor

Noah P. Dunham, Matthew S. Winston, Ritwika Ray et al. · Journal of the American Chemical Society · 2024 · 30 citations

Life Sciences, Biochemistry, Biotechnology +15

Holistic analytical characterization and risk assessment of residual host cell protein impurities in an active pharmaceutical ingredient synthesized by biocatalysts

Fengqiang Wang, Xuanwen Li, Michael D. Swanson et al. · Biotechnology and Bioengineering · 2022 · 12 citations

Pharmacy, Biochemistry, Pharmaceutical Analysis +13

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